Yusufari is a Local Government Area in Yobe State, Nigeria.

Its headquarters are in the town of Yusufari in the south-east of the area at 13°04′06″N 11°10′33″E. It shares a border in the north with The Republic of Niger.

It has an area of 3,928 km2 and a population of 111,086 at the 2006 census.

The postal code of the area is 630.